Michelle,
So I have always been a big fan of
Coronado Springs, but in your case I would say that
Port Orleans French Quarter might be a better fit. But it really is close. Some thoughts;
I think your kids will find both the pool and most of the the amenities in the main hotel building to be a bit better in Coronado Springs. But activities at both pools should be comparable. But the food court dining would be better for them at Port Orleans. The grab and go options seem superior, which will probably be more to their speed.
The theming is essentially a toss up, though I find that Coronado Springs has a greater elegance factor in most room themes. But they are close.
I think the access to transportation and location are the real tie breakers. For Coronado Springs everything is a bus ride away. But with Port Orleans French Quarter your family, or possibly even your kids on their own, can walk to explore another resort (Port Orleans Riverside), or better yet grab a scenic boat ride to the amazing array of shopping, dining, and entertainment of Downtown Disney.
BOTTOM LINE: Either is great, but for you I would go with Port Orleans French Quarter. I have stayed at both recently, so if you have any follow up questions, send them my way!
Have a magical vacation!